New Poems

Ushering in a new era for POEMS.

Li and colleagues are to be congratulated for conducting the first prospective clinical trial for POEMS syndrome, which treated 31 patients with 12 cycles of melphalan and dexamethasone.1 Although the choice of regimen is an old standard, this study is novel and important on several levels. First, it demonstrates that accrual for a trial for this very rare disease is possible. Second, the autho...

Mystic Poems, Poems of Enlightment

Is Syphilis a Potential New Factor of the POEMS Syndrome?

A 56‐year‐old man with a 9‐year history of progressive polyneuropathy was admitted to hospital, for feeling worse accompanied with chest discomfort and dyspnea in recent 1 month. In 2005, the patient started complaining of his limbs weakness and numbness then progressed to unable to walk. In 2006, the patient was diagnosed as chronic inflammatory demyelinating polyneuropathy (CIDP) by the local...

POEMS syndrome.

POEMS syndrome is a rare paraneoplastic syndrome secondary to a plasma cell dyscrasia. Recognition of the complex of a combination of peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasmaproliferative disorder, skin changes, papilledema, extravascular volume overload (peripheral edema, pleural effusions, ascites), sclerotic bone lesions, thrombocytosis, Castleman disease is the...

POEMS syndrome.

POEMS syndrome is the syndrome of Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and typical Skin changes. A 65-year-old lady presented with the 2-day-history of inability to walk, 4-month-history of progressive worsening of muscle weakness of both lower limbs and 1-year-history of progressive worsening of bilateral numbness of lower limbs. Nerve conduction study revealed gene...